Estrogen is a vital hormone in the human body, playing a significant role in reproductive health, bone density, cardiovascular function, and overall well-being. However, there are various factors that can lead to a reduction in estrogen levels. In this comprehensive post, we will explore the causes of estrogen hormone level reduction, considering both natural processes and external influences that can affect hormonal balance.

One of the most common causes of estrogen level reduction in women is menopause. Menopause is a natural biological process that typically occurs around the age of 45 to 55, marking the end of a woman’s reproductive years. During menopause, the ovaries gradually produce less estrogen and progesterone, leading to various physical and emotional changes, such as hot flashes, mood swings, and vaginal dryness.

Age-related Decline

Apart from menopause, aging itself can lead to a gradual decline in estrogen levels in both men and women. As individuals age, the production of sex hormones decreases, and this decline can impact various aspects of health and vitality.

Ovarian Disorders
Certain ovarian disorders, such as polycystic ovary syndrome (PCOS) and premature ovarian failure, can disrupt the normal functioning of the ovaries and result in reduced estrogen production. PCOS is characterized by hormonal imbalances, insulin resistance, and enlarged ovaries with small cysts. Premature ovarian failure, on the other hand, refers to the loss of normal ovarian function before the age of 40.

Surgical Menopause
Women who undergo surgical procedures such as bilateral oophorectomy (removal of both ovaries) may experience an abrupt and significant reduction in estrogen levels. This surgical menopause can lead to more severe menopausal symptoms than natural menopause.

Hormonal Medications
Certain medications, such as hormone therapy used to treat certain cancers (e.g., breast cancer, prostate cancer), can lower estrogen levels as a side effect. Additionally, some hormonal contraceptives, like certain types of birth control pills and intrauterine devices (IUDs), may influence hormone levels in women.

Malnutrition and Eating Disorders
Severe malnutrition and eating disorders, such as anorexia nervosa, can impact hormone production in both men and women. These conditions may lead to disruptions in the hypothalamic-pituitary-gonadal axis, affecting estrogen levels and reproductive function.

Chronic Stress
Prolonged exposure to chronic stress can influence hormonal balance. High levels of stress can lead to increased cortisol production, which may interfere with the normal secretion of sex hormones, including estrogen.

Environmental Toxins
Exposure to certain environmental toxins, such as endocrine-disrupting chemicals found in plastics, pesticides, and some consumer products, can interfere with hormonal regulation, potentially impacting estrogen levels.

Obesity has been linked to hormonal imbalances, including decreased estrogen levels in both men and women. Fat cells can produce estrogen, and excess body fat may lead to an overproduction of estrogen while reducing the body’s sensitivity to the hormone.

Chronic Illness
Certain chronic medical conditions, such as kidney disease, liver disease, and autoimmune disorders, can affect hormonal balance and lead to changes in estrogen levels.


Estrogen hormone level reduction can occur due to a variety of natural processes and external influences. Menopause, age-related decline, ovarian disorders, surgical interventions, medications, malnutrition, chronic stress, environmental toxins, obesity, and chronic illnesses can all impact hormonal balance and lead to changes in estrogen levels. Understanding these potential causes is essential for addressing hormonal imbalances and promoting overall health and well-being. If individuals experience significant hormonal disruptions or related symptoms, it is crucial to seek medical advice from qualified healthcare professionals for appropriate evaluation, diagnosis, and treatment.